Deoxyribonucleic Acid Encoding Research Articles

A two-parameter extended logistic chaotic map for modern image cryptosystems

In this paper, a novel Extended Logistic Chaotic Map (ELCM) with two control parameters is proposed. Overcoming the major drawback of the standard Logistic and other existing chaotic maps, the ELCM not only has infinite chaotic range as well as good ergodicity, but also has a simple structure just like the Logistic map, which greatly facilitates its practical implementation and becomes very suitable for today's real-time applications. Moreover, a new color image encryption scheme based on chaos concept, DNA (Deoxyribonucleic Acid) encoding and Convolutional Neural Network (CNN) is also presented. To perform a chaotic scrambling, the ELCM is however used at different stages of the encryption process. In addition, a pre-trained AlexNet CNN is used to generate a public key. After XORing with the secret key, the latter is used, on the one hand, to generate the initials values and the control parameters of the ELCM. On the other hand, it will be split into two keys in order to generate a random grayscale image, which will then be XORed with the three components (i.e., R, G and B) of the color plaintext image. Afterward, a permutation operation, DNA encoding, diffusion operation as well as bit reversion operation are then applied to the R, G and B components. The performance evaluation demonstrates that the ELCM not only has an infinite chaotic parameter range, but also exhibits a high chaotic complexity. Besides, experimental results as well as security analysis confirm that with NPCR of 99.6287%, the designed color image encryption scheme achieves an average entropy of 7.9975 and a near zero correlation (-0.0027). Furthermore, the proposed encryption scheme is in fact of higher security level in comparison to other schemes recently presented in the literature, thus making it highly suitable for today's real-time applications.

Color image encryption based on discrete memristor logistic map and DNA encoding

This paper proposes a color image encryption scheme with new features based on two-dimensional discrete memristor logistic map (2D-MLM), Deoxyribonucleic acid (DNA) encoding and multi-wing hyperchaotic systems. Firstly, the discrete memristor map and four-wing hyperchaotic system are used to generate various pseudo-random sequences. Secondly, the original image is processed in blocks, and DNA encoding and operation are performed on the sub-block image using multiple pseudo-random sequences. Finally, combining the pseudo-random sequence to diffuse the sub-block image and DNA decoding, we can get the encrypted image. The scheme generates a one-time key for each image, and uses multiple different sub-keys to increase the key space. The use of diverse pseudo-random sequences for image scrambling effectively avoids the security risks associated with using a single chaotic sequence. The key space of this algorithm reaches 2425, the information entropy of the ciphertext image is 7.9993, the number of pixels change rate (NPCR) and the uniformed average change intensity (UACI) reach 99.6095 % and 33.5089 %, and the inter-pixel correlation is close to zero. The simulation results prove that the proposed algorithm has good security against many potential attacks.

A RGB image encryption technique using chaotic maps of fractional variable-order based on DNA encoding

This paper presents a controller-based synchronization scheme in a leader-follower architecture for chaotic maps of fractional variable-order. The proposed scheme demonstrates successful synchronization of three different chaotic maps through simulation results. The implementation on Arduino UNO boards is used to showcase the relatively low algorithm complexity of the proposed scheme. Additionally, the paper explores a potential application of the proposed scheme in an RGB image encryption system, leveraging the chaotic behavior of the system for pseudo-random sequence generation. The encoding scheme utilizes the complementary property of Deoxyribonucleic acid (DNA) molecule bases. The presented encryption scheme employs the variable-order of the fractional derivative as a key for improved safety. This enhancement improves the methodology resistance against brute-force attacks while maintaining resilience against other cryptoanalysis techniques.

Study on DNA Storage Encoding Based IAOA under Innovation Constraints

With the informationization of social processes, the amount of related data has greatly increased, making traditional storage media unable to meet the current requirements for data storage. Due to its advantages of a high storage capacity and persistence, deoxyribonucleic acid (DNA) has been considered the most prospective storage media to solve the data storage problem. Synthesis is an important process for DNA storage, and low-quality DNA coding can increase errors during sequencing, which can affect the storage efficiency. To reduce errors caused by the poor stability of DNA sequences during storage, this paper proposes a method that uses the double-matching and error-pairing constraints to improve the quality of the DNA coding set. First, the double-matching and error-pairing constraints are defined to solve problems of sequences with self-complementary reactions in the solution that are prone to mismatch at the 3' end. In addition, two strategies are introduced in the arithmetic optimization algorithm, including a random perturbation of the elementary function and a double adaptive weighting strategy. An improved arithmetic optimization algorithm (IAOA) is proposed to construct DNA coding sets. The experimental results of the IAOA on 13 benchmark functions show a significant improvement in its exploration and development capabilities over the existing algorithms. Moreover, the IAOA is used in the DNA encoding design under both traditional and new constraints. The DNA coding sets are tested to estimate their quality regarding the number of hairpins and melting temperature. The DNA storage coding sets constructed in this study are improved by 77.7% at the lower boundary compared to existing algorithms. The DNA sequences in the storage sets show a reduction of 9.7-84.1% in the melting temperature variance, and the hairpin structure ratio is reduced by 2.1-80%. The results indicate that the stability of the DNA coding sets is improved under the two proposed constraints compared to traditional constraints.

Novel medical image cryptogram technology based on segmentation and DNA encoding

This paper proposes a novel medical image cryptogram technology based on a fast and robust fuzzy C-means clustering image segmentation method and deoxyribonucleic acid encoding. In our method, first, the medical image is divided into background areas and regions of interest utilizing fuzzy C-means clustering image segmentation, which increases the encryption efficiency by about 60% when the background area is discarded. Second, some low-value pixels are also discarded in regions of interest to further reduce the encryption time. Third, a 4-dimensional hyperchaotic system has been improved. Furthermore, the hyperchaotic system and deoxyribonucleic acid encoding are utilized to encrypt the medical image. Finally, lossless encryption and fast encryption are done for different purposes. The experimental results demonstrate that the proposed algorithm has appealing encryption performance and the histogram and scatter graphs are governed by approximately uniform distribution. The NPCR and UACI of plaintext sensitivity and the key sensitivity are close to 99.6094% and 33.4635% respectively, which cause robustness against noise and clipping attacks.

Medical Image Encryption by Content-Aware DNA Computing for Secure Healthcare

There exists a rising concern on security of healthcare data and service. Even small lost, stolen, displaced, hacked, or communicated in personal health data could bring huge damage to patients. Therefore, we propose a novel content-aware deoxyribonucleic acid (DNA) computing system to encrypt medical images, thus guaranteeing privacy and promoting secure healthcare environment. The proposed system consists of sender and receiver to perform tasks of encryption and decryption, respectively, where both contain the same structure design, but perform opposite operations. In either sender or receiver, we design a randomly DNA encoding and a content-aware permutation and diffusion module. Considering introducing random mechanism to increase difficulty of cracking, the former module builds a random encryption rule selector in DNA encoding process by randomly mapping quantity of medical image pixels to outputs. Meanwhile, the latter module constructs a permutation sequence, which not only encodes information of pixel values, but also involves redundant correlation between adjacent pixels located in a patch. Such design brings awareness property of medical image content to greatly increase complexity in cracking by embedding semantical information for encryption. We demonstrate that the proposed system successfully improve cybersecurity of medical images against various attacks in robustness and effectiveness when transmitting data in wireless broadcasting scenarios.

Memristor-Based Hyperchaotic System and DNA Encoding Based Image Encryption Application on LabVIEW

With the advancement of technology, the growth of multimedia and communication tools has sped up data transfer, and guaranteeing image security has become a crucial concern, particularly during the transmission and storage of images. So, when images are sent over a public network, they should be encrypted before being sent to the receiving part. In this study, a memristor-based encryption system with Deoxyribonucleic acid (DNA) coding is proposed on the LabVIEW platform to ensure information security. Firstly, memrsitor based hyperchaotic system is used for chaotic sequence. The images are encrypted using the DNA and XOR arithmetic process on the LabVIEW platform. A memristor-based hyperchaotic system and the combination of techniques used are aimed at encrypting the image securely. In addition, security tests; histogram analysis, correlation analysis, differential attack, and entropy analysis, are performed on the proposed system and the results are presented. The aforementioned methods are thoroughly examined and tested to determine their efficacy. It has been determined that the proposed encryption schemes are effective and can therefore be used in real-time applications.

DNA Computing with Water Strider Based Vector Quantization for Data Storage Systems

The exponential growth of data necessitates an effective data storage scheme, which helps to effectively manage the large quantity of data. To accomplish this, Deoxyribonucleic Acid (DNA) digital data storage process can be employed, which encodes and decodes binary data to and from synthesized strands of DNA. Vector quantization (VQ) is a commonly employed scheme for image compression and the optimal codebook generation is an effective process to reach maximum compression efficiency. This article introduces a new DNA Computing with Water Strider Algorithm based Vector Quantization (DNAC-WSAVQ) technique for Data Storage Systems. The proposed DNAC-WSAVQ technique enables encoding data using DNA computing and then compresses it for effective data storage. Besides, the DNAC-WSAVQ model initially performs DNA encoding on the input images to generate a binary encoded form. In addition, a Water Strider algorithm with Linde-Buzo-Gray (WSA-LBG) model is applied for the compression process and thereby storage area can be considerably minimized. In order to generate optimal codebook for LBG, the WSA is applied to it. The performance validation of the DNAC-WSAVQ model is carried out and the results are inspected under several measures. The comparative study highlighted the improved outcomes of the DNAC-WSAVQ model over the existing methods.

An Efficient Color-Image Encryption Method Using DNA Sequence and Chaos Cipher

Nowadays, high-resolution images pose several challenges in the context of image encryption. The encryption of huge images’ file sizes requires high computational resources. Traditional encryption techniques like, Data Encryption Standard (DES), and Advanced Encryption Standard (AES) are not only inefficient, but also less secure. Due to characteristics of chaos theory, such as periodicity, sensitivity to initial conditions and control parameters, and unpredictability. Hence, the characteristics of deoxyribonucleic acid (DNA), such as vast parallelism and large storage capacity, make it a promising field. This paper presents an efficient color image encryption method utilizing DNA encoding with two types of hyper-chaotic maps. The proposed encryption method comprises three steps. The first step initializes the conditions for generating Lorenz and Rossler hyper-chaotic maps using a plain image Secure Hash Algorithm (SHA-256/384). The second step performs a confusion procedure by scrambling the three components of the image (red, green, and blue) using Lorenz hyper-chaotic sequences. Finally, the third step combines three approaches to encrypt the scrambled components for diffusion: DNA encoding/decoding, addition operation between components, and XORing with Rossler hyper-chaotic sequences. The simulation results indicate that the suggested encryption algorithm satisfies the requirements of security. The entropy value of confusion and diffusion is 7.997, the key space is 2²⁰⁰, and the correlation coefficient is nearly zero. The efficacy of the proposed method has been verified through numerous evaluations, and the results show its resistance and effectiveness against several attacks, like statistical and brute-force attacks. Finally, the devised algorithm vanquishes other relevant color image encryption algorithms.

Secure DNA-Coding Image Optical Communication Using Non-Degenerate Hyperchaos and Dynamic Secret-Key

With the aim of tackling insufficient security in the chaotic encryption algorithm for digital images in the Optical Access Network, a color image encryption scheme combining non-degenerate discrete hyperchaotic system and deoxyribonucleic acid (DNA) dynamic encoding is proposed. First, a new non-degenerate hyperchaotic system is constructed with all positive Lyapunov and more complex dynamic characteristics. Furthermore, the key sequence based on non-degenerate hyperchaotic system is generated using plaintext correlation to achieve the effect of a dynamic secret key. Next, a binary bit-planes permutation is performed on the image using one of the key sequences. Then, the chaotic key sequence is used to sequentially perform DNA encoding, obfuscation, and decoding. Finally, a binary bit-planes obfuscation is performed to obtain the final ciphertext. The research results show that the non-degenerate chaotic sequence can pass the NIST 800-22 test, and the corresponding encryption algorithm can resist various common attacks and has a strong anti-interference ability. In addition, the algorithm is verified on ARM-Embedded, which proves that the encryption system proposed in this paper is a feasible secure communication technology scheme. Therefore, the scheme proposed in this paper is helpful to provide new ideas for the design and application of high-security cryptosystem in optical access network.

Network intrusion detection based on DNA spatial information

There is an ever-increasing risk of illegal access-induced Network Intrusion (NI), which calls for prompt detection of illegal network behavior through profound Network Traffic (NT) analyses. However, current intrusion detection methods are limited in accuracy due to insufficient data standardization. This paper puts forward a deoxyribonucleic acid (DNA)-Spatial Information (SI) method to overcome these limitations. A DNA encoding model is formed, which defines a mapping relationship between NT attributes and nucleobases to reconstruct NT samples expressed as DNA sequences. Then, a feature extraction algorithm is constructed that deduces a Spatial Information Feature Matrix (SIFM) to represent sequence statistical features. A Random Forest (RF) algorithm is adopted as a matching process to determine NI behaviors considering the detection efficiency. Following experiments evaluate its method performance on two datasets, NSL-KDD and UNSW-NB15. Results demonstrate that DNA-SI obtains better results than state-of-the-art works, where the accuracy, F1-score, recall, far are 95.75%, 94.41%, 94.12%, 3.26% and 92.30%, 92.78%, 89.82%, 4.66% respectively. The fact that it is insusceptible to minority intrusion samples is another point worth attention. In sum, this quick and accurate network intrusion detection points to a new orientation for safeguarding network security.

Image Encryption Using a Spectrally Efficient Halton Logistics Tent (HaLT) Map and DNA Encoding for Secured Image Communication.

With the advancement of technology worldwide, security is essential for online information and data. This research work proposes a novel image encryption method based on combined chaotic maps, Halton sequence, five-dimension (5D) Hyper-Chaotic System and Deoxyribonucleic Acid (DNA) encoding. Halton sequence is a known low-discrepancy sequence having uniform distribution in space for application in numerical methods. In the proposed work, we derived a new chaotic map (HaLT map) by combining chaotic maps and Halton sequence to scramble images for cryptography applications. First level scrambling was done by using the HaLT map along with a modified quantization unit. In addition, the scrambled image underwent inter- and intra-bit scrambling for enhanced security. Hash values of the original and scrambled image were used for initial conditions to generate a 5D hyper-chaotic map. Since a 5D chaotic map has complex dynamic behavior, it could be used to generate random sequences for image diffusion. Further, DNA level permutation and pixel diffusion was applied. Seven DNA operators, i.e., ADD, SUB, MUL, XOR, XNOR, Right-Shift and Left-Shift, were used for pixel diffusion. The simulation results showed that the proposed image encryption method was fast and provided better encryption compared to ‘state of the art’ techniques. Furthermore, it resisted various attacks.

A Novel Medical Image Encryption Using R鰏sler System

The technological advances made possible by the Internet, coupled with the unforeseen critical circumstances set in motion by the Covid-19 pandemic, have greatly increased the generation and transmission of medical images every day. Medical image transmission over an unsecured public network threatens the privacy of sensitive patient information. We have, in this paper, designed a new secure color medical image encryption algorithm based on binary plane decomposition, DNA (deoxyribonucleic acid) computing, and the chaotic Rössler dynamical system. At first, a bit-by-bit swap is performed on twenty four binary planes of the input image and encoded using DNA encoding rules. Thereafter, the Rössler system is used to modify the pixel values of the encoded image, which is subsequently decoded. Finally, the ciphered image is obtained by pixel-by-pixel permutation using position sequences. An innovative approach is used to compute keys from the color components of the input image. Extensive performance experiments of the proposed technique is conducted with metrics such as key sensitivity, key space, correlation coefficients (horizontal, diagonal and vertical directions), histograms, information entropy, number of pixel changes rate (NPCR), information entropy, unified average changing intensity (UACI), and encryption time. Comparative analyses have demonstrated that the proposed algorithm is fast, robust and competitive.

A Novel Hybrid Encryption Method Based on Honey Encryption and Advanced DNA Encoding Scheme in Key Generation

Nowadays, increased information capacity and transmission processes make information security a difficult problem. As a result, most researchers employ encryption and decryption algorithms to enhance information security domains. As it progresses, new encryption methods are being used for information security. In this paper, a hybrid encryption algorithm that combines the honey encryption algorithm and an advanced DNA encoding scheme in key generation is presented. Deoxyribonucleic Acid (DNA) achieves maximal protection and powerful security with high capacity and low modification rate, it is currently being investigated as a potential carrier for information security. Honey Encryption (HE) is an important encryption method for security systems and can strongly prevent brute force attacks. However, the traditional honeyword encryption has a message space limitation problem in the message distribution process. Therefore, we use an improved honey encryption algorithm in our proposed system. By combining the benefits of the DNA-based encoding algorithm with the improved Honey encryption algorithm, a new hybrid method is created in the proposed system. In this paper, five different lookup tables are created in the DNA encoding scheme in key generation. The improved Honey encryption algorithm based on the DNA encoding scheme in key generation is discussed in detail. The passwords are generated as the keys by using the DNA methods based on five different lookup tables, and the disease names are the input messages that are encoded by using the honey encryption process. This hybrid method can reduce the storage overhead problem in the DNA method by applying the five different lookup tables and can reduce time complexity in the existing honey encryption process.

Optical color image encryption scheme with a novel DNA encoding algorithm based on a chaotic circuit

An optical setup with a unique color image cryptography technique employing a chaotic system is suggested in this study. For this purpose, deoxyribonucleic acid (DNA) encoding is used as an encryption method. Rössler attractor is employed as a chaotic system and it consists of three differential equations. In order to implement the chaotic system by analog electronic components, a circuit design including operational transconductance amplifier (OTA) is also suggested. Circuit simulations have been performed utilizing LT spice program. In the proposed study, the number of DNA encoding rules has excessively been increased compared to previous studies on DNA encoding technique. Thus, the security of the encryption scheme is enhanced. Numerous security tests such as correlation coefficient, histogram, Shannon entropy, secret key and initial condition sensitivities, plaintext and ciphertext attacks and differential attack have been carried out to evaluate functioning of the introduced cryptography algorithm. The numerical test results prove that the suggested encryption algorithm can resist statistical and differential attacks. Moreover, the cryptology scheme indicates the behavior of sensitivity to initial condition and secret key. The presented algorithm has great performance from the point of encoding rules number and being robust against differential attack. Moreover, enhanced double random phase encoding (DRPE) technique is used in optical stage of the study. By modifying the conventional DRPE method, correlation value between R, G, B components for same pixel have extremely reduced. All numerical analyses regarding chaotic system and encryption scheme have been performed in MATLAB program.

Block color image encryption algorithm based on elementary cellular automata and DNA sequence operations

A block color image encryption algorithm based on chaotic system, elementary cellular automata (ECA), and deoxyribonucleic acid (DNA) sequence operations is proposed. The architecture is comprised of forward-diffusion, permutation, and backward-diffusion. First, the red, green, and blue components of a color image are converted into three DNA matrices by DNA encoding rule. Exclusive OR (XOR) operation is applied between the DNA coding chaotic sequence generated by the improved Henon map and three DNA matrices. Second, the large DNA matrix, composed of three DNA matrices, is divided into several small blocks with unequal sizes. ECA is employed to scramble the positions of these blocks. Finally, DNA computations are introduced to diffuse three permutated DNA matrices. In addition, initial values and system parameters of the chaotic system are calculated from the secure hash algorithm (SHA-256) hash value of the plain image and the given parameters. Both DNA encoding and ECA order rules rely on plaintext information. Therefore, the proposed algorithm is highly sensitive to plain image. Simulation results and security analyses demonstrate that our algorithm achieves excellent security performance and acceptable running time.

Nucleic acid vaccines and CpG oligodeoxynucleotides for allergen immunotherapy.

Molecular forms of allergen-specific immunotherapy (AIT) are continuously emerging to improve the efficacy of the treatment, to shorten the duration of protocols and to prevent any side effects. The present review covers the recent progress in the development of AIT based on nucleic acid encoding allergens or CpG oligodeoxynucleotides (CpG-ODN). Therapeutic vaccinations with plasmid deoxyribonucleic acid (DNA) encoding major shrimp Met e 1 or insect For t 2 allergen were effective for the treatment of food or insect bite allergy in respective animal models. DNA expressing hypoallergenic shrimp tropomyosin activated Foxp3+ T regulatory (Treg) cells whereas DNA encoding For t 2 down-regulated the expression of pruritus-inducing IL-31. Co-administrations of major cat allergen Fel d 1 with high doses of CpG-ODN reduced Th2 airway inflammation through tolerance induction mediated by GATA3+ Foxp3hi Treg cells as well as early anti-inflammatory TNF/TNFR2 signaling cascade. Non-canonical CpG-ODN derived from Cryptococcus neoformans as well as methylated CpG sites present in the genomic DNA from Bifidobacterium infantis mediated Th1 or Treg cell differentiation respectively. Recent studies on plasmid DNA encoding allergens evidenced their therapeutic potential for the treatment of food allergy and atopic dermatitis. Unmethylated or methylated CpG-ODNs were shown to activate dose-dependent Treg/Th1 responses. Large clinical trials need to be conducted to confirm these promising preclinical data. Moreover, tremendous success of messenger ribonucleic acid (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 must encourage as well the re-exploration of mRNA vaccine platform for innovative AIT.

A novel auto-encoder induced chaos based image encryption framework aiding DNA computing sequence

The day-to-day progress in communication plays a vital role in transmitting millions and trillions of data through the unsecured network channels. It creates a way where the user’s data becomes the victim of various security threats. Among those users’ data, images act as primary data, and its encryption security methodologies are fascinating. The conventional encryption techniques don’t work well against the various other hidden security threats but require substantial computational time and cost with poor permutation performance. Hence to deal with this, an auto-encoder induced DNA (Deoxyribonucleic acid) sequence via chaotic image encryption framework is designed in our proposed work. It integrates the properties of DNA encoding and the chaotic maps to handle the data losses effectively and resist several attacks such as statistical attacks, chosen-plaintext attacks, etc. Moreover, an auto-encoder is used to control the data noises, thereby ensuring a better encryption performance. Here, the auto-encoder is activated to generate a permuted image with less time complexity and noise. A secret key is then initialized with the aid of SHA-256. Finally, image encryption and decryption are achieved, followed by the successful transmission of data over a digital network. The performance of the proposed work is analyzed with varied metrics to strengthen its efficiency over the prior techniques.

Secure and Efficient Image Cryptography Technique using Choas and DNA Encoding Methodology

In this era of the digital world, handling digital data with a secure passion is more important. At the height of maximum interest with the attainment of the data confidentiality with the miniature information is the tedious and most challenging concern of the system with the data handling and operating in the real-time environment. With the latest data confidentiality security model, such as image encryption over the communication networks in the distributed data environment, advanced hacking efforts such as cropping attack, brute force, differential, mathematical, and many more need to be addressed. In terms of bit scrambling, the security function plays a vital role in the pixel-based approach with minimum pixels are followed in the current security model  for a better correlation with the available pixels with the continued higher runtime complexity. In this research paper, along with the DNA encoding process, an efficient image cryptographic technique is shown with the reduced runtime complexity. The discussion in the article begins with the chaotic sequence EIIS (Efficient Image Information Scrambling) method. Progressed with the DNA (Deoxyribo Nucleic Acid) encoding is done with the data for resistance against different kinds of attacks by considering the suitable parameters from the existing security models.

Robust medical image encryption based on DNA-chaos cryptosystem for secure telemedicine and healthcare applications

The security of healthcare and telemedicine systems is a critical issue that must be significantly investigated. Several smart telemedicine applications are expected to be adopted in the medical sector in the incoming years. Healthcare smart products that are connected through Internet to be accessible anytime and anywhere are expected to deal with critical and confidential information such as personal medical images. Therefore, medical image encryption is an important task in telemedicine and healthcare applications. This paper presents an efficient cryptosystem for medical image security based on exploiting the advantages of the de-oxyribo nucleic acid (DNA) rules and chaos maps. In the proposed medical image cryptosystem, logistic chaos map, piecewise linear chaotic map (PWLCM), and DNA encoding are employed. The PWLCM is employed to generate a secret key image. Then, the DNA rules are utilized for encoding the secret key image and the input plain image by rows that are encoded with the logistic chaos map. After that, the proposed logistic map is employed to obtain an intermediate image as another secret key image to set DNA functions row-by-row on the coded original image. Moreover, the intermediate image is decoded in the following stage. Finally, the previous actions are iterated through image columns once again to obtain the best ciphered image. The experimental results reveal that the suggested cryptosystem has a high security with an acceptable processing time. In addition, it can resist various kinds of attacks, such as known-plaintext and chosen-plaintext attacks.